Is Remdesivir a Rambaan remedy for Covid?

Last week, the district collector called a meeting. The meeting was attended, among other, by local MLAs, MPs, bureaucrats and doctors from the two medical colleges in the district. The second wave had peaked and more patients were seeking hospital admissions than the hospital could provide. ICU beds were at a premium and hospitals were … Read more

Politics of Science in a Pandemic

In 2020, Covid virus— a black swan— wreaked havoc across the globe, killing more than 1.5 million people, infecting many more and causing economic devastation. And although research developments progressed very fast in 2020, the pandemic set the course of science afire. The coronavirus spread. And as fast did the scientists, researchers and public health activists move.  No … Read more

Make hay while the sun shines: Unproven COVID drugs in India

India has the world’s second-largest COVID-19 outbreak. India desperately needs effective treatments. But the way the country’s drug regulator is handling potential therapies concerns many of us. The Drugs Controller General of India (DCGI) has approved several repurposed drugs for ‘restricted emergency use’ for treating the disease. On what basis were these drugs approved? Was … Read more

Hydroxychloroquine and Covid

My colleagues and I wrote our concern in Lancet Infect Dis about the inappropriate and irrational use of Hydroxychloroquine for preventing and treating Covid in India. We wrote this when the pandemic had just started. The Indian Council of Medical Research, under the Ministry of Health and Family Welfare, has recommended chemoprophylaxis with hydroxychloroquine for … Read more

Covid and Community Transmission

I see three challenges ahead vis-à-vis COVID-19 in India’s rural areas. First, many rural healthcare workers are exhausted and burned out. Second, lifestyle diseases like diabetes, high blood-pressure and heart problems have become more common in rural India in the last decade or so. Third, officials and healthcare workers have to contend with the spectre … Read more

Ulhas, the writer

Some physicians are known to write creatively, taking up pen alongside their stethoscopes. Ulhas Jajoo belongs to that creed. A Writer-physician or a physician-writer. This week, Ulhas had his four Hindi books published. He writes about the people he admired, and those who shaped his life and times. He also picks up thoughts and narrations … Read more

Covid: Evidence, Ethics and Economics

This afternoon I spoke on several issues that influence our thought processes when we see patients with Covid19- in the community, in the hospital OPD, wards or ICUs. How should we design our therapy? Should we allow ourselves to prescribe untested and unproven therapies because the atmosphere is filled with fear, desperation and panic? What … Read more

Clinical Trials in Covid: Ethics and Practice

Fear. Panic. Desperation.  Came Covid and most doctors began to prescribe anti-Covid drugs based not on scientific research, but based on anecdotes, media stories, newspapers, TV channels and promotion of drugs by the drug industry. The virus pushed the Evidence-based medicine to the back seat. Physicians were either reluctant to— or didn’t know how to— … Read more