SP Kalantri

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Covid

Remdesivir: Much ado about nothing?

Remdesivir. Hydroxychloroquine apart, no drug during the current pandemic created as much controversy, generated as much hope, led to as much black marketing and eniced as many physicians and people as Remdesivir did. I was not sure if remdesivir indeed reduced the chances of dying in hospitalised patients and wondered if the hype and hope …

Covid

Make hay while the sun shines: Unproven COVID drugs in India

India has the world’s second-largest COVID-19 outbreak. India desperately needs effective treatments. But the way the country’s drug regulator is handling potential therapies concerns many of us. The Drugs Controller General of India (DCGI) has approved several repurposed drugs for ‘restricted emergency use’ for treating the disease. On what basis were these drugs approved? Was …

Covid

COVID-19: The need for evidence-based medicine

A number of old drugs approved for other diseases are being “repurposed” and tested for their safety and efficacy in COVID-19, in systematic clinical trials. They have emergency approval for use in COVID-19, but most are not yet proven for this use. Some drugs have received approval without adequate testing. Other drugs are being used …

Covid

The many questions about Favipiravir

The Drugs Controller General of India (DCGI) has approved Glenmark Pharmaceuticals, an Indian pharmaceutical company, to sell generic versions of Favipiravir for the treatment of COVID-19. This drug, originally invented by a Japanese company, was meant to treat influenza. After the outbreak of COVID-19, doctors in China and Russia started using it to treat COVID-19 …

Drugs

Getting the Medicines Right: Rational Prescribing

Why should we insist on rational use of medicines?  Because we ought to ensure that our patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them. Irrational use of medicines is a major problem worldwide. WHO …