Some research studies make you sit up and take notice when you eye their titles and read the findings. The Lancet study published on 31 October 2022 is one such. A study everyone entering an OT must read. Why did I like this study? Because, hundreds of thousands of studies are published every year. But …
EBM
The Many Faces of Molnupiravir
Molnupiravir. Another drug that has created a lot of hype or hope among public. But does it really deliver what it promises?
Have scientific bodies failed us?
The ICMR has increasingly drawn criticism from India’s doctors and scientists, who have questioned its drug recommendations & lack of transparency on data related to variants. Countrywide, doctors started writing these prescriptions, which artificially inflated the cost for Covid management,” I said. “Big Pharma was laughing all the way to the bank and ultimately the …
Cost of Curing Covid
High hospital bills and black marketing of drugs and oxygen make the treatment of Covid-19 prohibitively expensive. Malini Aisola, co-convenor of the All India Drug Action Network, ET’s Kiran Somvanshi and I discuss the flaws in the existing setup and the steps to fix the financial burden of Covid-19.
Remdesivir: Much ado about nothing?
Remdesivir. Hydroxychloroquine apart, no drug during the current pandemic created as much controversy, generated as much hope, led to as much black marketing and eniced as many physicians and people as Remdesivir did. I was not sure if remdesivir indeed reduced the chances of dying in hospitalised patients and wondered if the hype and hope …
Covid19. Evidence based management for hospitalised patients
I designed an evidence-based management protocol for managing patients admitted to our teaching hospital with Covid19. The concept was minimalist: excluding irrational, untested, unproven therapies and focusing only on those which have been shown to work in large randomised trials. Here is a YouTube link to the powerpoint presentation:
Covid and EBM- or lack of it…
The novel anti-Covid medicines look promising and appealing, but I’d urge caution in interpreting the study results…
Is Remdesivir a Rambaan remedy for Covid?
Last week, the district collector called a meeting. The meeting was attended, among other, by local MLAs, MPs, bureaucrats and doctors from the two medical colleges in the district. The second wave had peaked and more patients were seeking hospital admissions than the hospital could provide. ICU beds were at a premium and hospitals were …
Make hay while the sun shines: Unproven COVID drugs in India
India has the world’s second-largest COVID-19 outbreak. India desperately needs effective treatments. But the way the country’s drug regulator is handling potential therapies concerns many of us. The Drugs Controller General of India (DCGI) has approved several repurposed drugs for ‘restricted emergency use’ for treating the disease. On what basis were these drugs approved? Was …
Covid: Evidence, Ethics and Economics
This afternoon I spoke on several issues that influence our thought processes when we see patients with Covid19- in the community, in the hospital OPD, wards or ICUs. How should we design our therapy? Should we allow ourselves to prescribe untested and unproven therapies because the atmosphere is filled with fear, desperation and panic? What …